中华麻醉在线
您当前位置:主页 > 热点专题 > 中国发表SCI论文汇总 >

J Int Med Res:Effect of creatine phosphate sodium on bispectral index and recovery quality during the general anaesthesia emergence period in elderly patients: A randomized, double-blind, placebo-controlled trial.

2018-08-30 10:18  来源:未知  编辑:高国雷   点击:
 
Wang W1Yu WY1Lv J1Chen LH2Li Z3.

Author information

1
1 Department of Anaesthesiology, Jiangning Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu Province, China.
2
2 Department of Anaesthesiology, First People's Hospital of Shanghai Affiliated to Nanjing Medical University, Shanghai, China.
3
3 Key Laboratory of Modern Toxicology (Ministry of Education), School of Public Health, Nanjing Medical University, Nanjing, Jiangsu Province, China.

Abstract

Objective To evaluate the effect of creatine phosphate sodium on bispectral index (BIS) and recovery quality during the general anaesthesia emergence period in elderly patients. Methods This randomized, double-blind, placebo-controlled study enrolled patients undergoing transabdominal cholecystectomy under general anaesthesia. Patients were randomly assigned to receive either creatine phosphate sodium (1.0 g/100 ml 0.9% saline; group P) or 100 ml 0.9% saline (group C) over 30 minutes during surgical incision. The BIS values were recorded at anaesthesia induction (T0), skin incision (T1), cutting the gallbladder (T2), suturing the peritoneum (T3), skin closure (T4), sputum suction (T5), extubation (T6) and 1 min (T7), 5 min (T8), 10 min (T9), and 15 min (T10) after extubation. The anaesthesia duration, operation time, waking time, extubation time, consciousness recovery time, time in the postanaesthesia care unit (PACU), and the Steward recovery scores at T7, T8, T9 and T10 were recorded. Results A total of 120 elderly patients were randomized equally to the two groups. Compared with group C, the BIS values were significantly higher in group P at T5, T6, T7 and T8; and the Steward recovery scores at T7 and T8 were significantly higher in group P. The waking time, extubation time, consciousness recovery time and time in the PACU were significantly shorter in group P compared with group C. Conclusion Creatine phosphate sodium administered during transabdominal cholecystectomy can improve BIS values and recovery following general anaesthesia in elderly patients.

KEYWORDS:

Creatine phosphate sodium; bispectral index; recovery quality


相关推荐
网友评论
请自觉遵守互联网相关的政策法规,严禁发布色情、暴力、反动的言论。
评价:
用户名: 验证码: 点击我更换图片
 
Copyright 中华麻醉在线 All rights reserved
地址:北京市东城区东四西大街42号中华医学会南楼2单元222室麻醉学分会办公室 邮编:100710
联系人:白雪   电话:010-85158614   传真:010-85158753   京ICP备14001125
360网站安全检测平台